Citeline and Norstella Unite to Offer Life Sciences Clients a Full Suite of Commercial and Clinical Solutions

The new organization will help life sciences companies improve strategic decision-making and accelerate the mission of smoothing access to therapy from pipeline to patient

Yardley, PA, June 28, 2022 (GLOBE NEWSWIRE) — Norstella, an organization that helps life sciences companies navigate the complexities of the drug life cycle, and Citeline (formerly Pharma Intelligence)—a leading provider of specialist intelligence, data and software for clinical trials, drug development and regulatory compliance—have announced an agreement to merge the companies.

By uniting Norstella, which is comprised of four prominent pharmaceutical solutions providers—EvaluateMMITPanalgo and The Dedham Group—with Citeline, the combined company will be well positioned to help life sciences companies reach patients faster by providing clients with the intelligence and answers they need from early clinical development through to commercialization. This move reflects the shared goal of becoming an end-to-end solution provider, helping patients access life-saving therapies.

As life sciences companies drive innovation toward more specialized therapeutics across all disease areas including oncology and rare disease, and patient populations become more targeted, they need to make critical decisions about how to bring the right drugs to market, how to construct clinical trials leveraging the latest innovations in real-world data and data science—and with end points that consider future payer reimbursement decisions—and, ultimately, how to reach patients in need.

“Accelerating innovation and ensuring that every patient gets the therapy that they need is our North Star,” said Norstella CEO Mike Gallup. “By bringing clinical and commercial intelligence together—along with real-world data—the combined company will be well positioned to deliver on its mission.”

Together, Norstella and Citeline will play a critical role in helping pharmaceutical manufacturers plan for and overcome barriers to access, not just during clinical trials but at every stage in the drug development life cycle. Citeline’s solutions, including its portfolio of clinical trial products, provide insights that improve the speed and efficiency of clinical trials and reduce risk. Now, the Citeline solutions—along with MMIT’s PAR data and other complementary Norstella data assets—can be powered by Panalgo’s Instant Health Data Analytics platform to provide transformative answers that will improve workflow and decision-making and, ultimately, help products get to market and to patients quicker than ever before.

“At Citeline, our mission is to accelerate the connection of treatments to patients and patients to treatments. Ultimately, this marriage of commercial and clinical capabilities will advance the mission and enable the pharmaceutical C-suite to manage portfolio strategy like never before,” said Ramsey Hashem, CEO, and Jay Nadler, Executive Chair, of Citeline. “This includes deciding which drug to bring to market, what new indications to pursue for a drug and how to target patients for clinical trials more quickly and with reduced cost. And now, this includes understanding how to design clinical trials that yield the types of data that payers need to make appropriate reimbursement and formulary decisions.”

“It’s about making a difference in the lives of patients,” said Gallup. “This move will help us make our vision of a more innovative, accessible healthcare marketplace a reality.”

The merger is expected to close in the second half of 2022 subject to customary closing conditions and regulatory approvals.

About Norstella
At Norstella, our mission is simple: to help patients gain access to life-saving therapies. Norstella consists of several prominent organizations—Evaluate, MMIT, Panalgo and The Dedham Group—that have united to offer a full range of pharmaceutical consultancy services and solutions. As one organization, Norstella provides life sciences clients with the right tools and expertise to navigate complexities at each step of the drug development life cycle, from pipeline to patient. For more information, visit Norstella and follow on LinkedIn.

About Citeline
Citeline (formerly Pharma Intelligence) powers a full suite of complementary business intelligence offerings to meet the evolving needs of health science professionals to accelerate the connection of treatments to patients and patients to treatments. These patient-focused solutions and services deliver and analyze data used to drive clinical, commercial, and regulatory related-decisions and create real-world opportunities for growth.

Our global teams of analysts, journalists and consultants keep their fingers on the pulse of the pharmaceutical, biomedical and medtech industries, covering it all with expert insights: key diseases, clinical trials, drug R&D and approvals, market forecasts and more. For more information on one of the world’s most trusted health science partners, visit Citeline.

Melody Udell
Norstella
312-618-5968
melody.udell@norstella.com

Blair Dawson
Citeline
919-413-4616
blair.dawson@informa.com

Seegene develops PCR test to detect monkeypox virus

  • Assay targets monkeypox virus and can deliver results in 90 minutes
  • Company swiftly rolls out product using its automated assay development system
  • “Seegene will strive to make accurate tests for emerging viruses to help prevent future pandemics”

SEOUL, South Korea, June 28, 2022 /PRNewswire/ — Seegene Inc. (KQ965390), South Korea’s leading molecular diagnostics (MDx) company has developed a PCR test to detect the monkeypox virus. The Novaplex™ MPXV Assay, which specifically targets the monkeypox virus, was swiftly developed using the company’s AI-based automated test development system, known as SGDDS (Seegene Digitalized Development System), and technologies refined over 20 years of MDx expertise.

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The World Health Organization says the monkeypox virus is an “evolving health threat that requires collective attention and coordinated action,” calling on member states to step up surveillance, contact tracing and testing. The monkeypox virus has been detected in over 50 nations, with South Korea confirming its first case last week. The strain currently circulating in the Northern Hemisphere has an estimated fatality rate of between 3-6 percent and is considered especially dangerous for children and those with weak immune systems.

As with many infectious diseases, accurate diagnosis is crucial as treatments are more effective in the early stages of infection. This makes timely PCR testing vital, especially for individuals with a suspected case, as the incubation period for the monkeypox infection ranges between five to 21 days.

The Novaplex™ MPXV Assay can identify positive cases of the monkeypox virus in 90 minutes. The company swiftly developed the product to help curb the worldwide spread. Seegene plans to provide the assays to countries that have detected the virus.

“The monkeypox virus outbreak shows that endemic viruses can rapidly spread to the rest of the world and it’s a warning that new pandemics can emerge and threaten our lives at any time,” said Dr. Jong-Yoon Chun, CEO of Seegene. “We will continue our efforts to develop products that can accurately diagnose any virus to help prevent new infectious diseases from taking hold and becoming a pandemic.”

Logo – https://mma.prnewswire.com/media/1357790/Seegene_logo_Logo.jpg

Hitachi Energy and Petrofac to collaborate in growing offshore wind market

Collaboration combines complementary technologies and expertise of both companies to increase customer value and help accelerate the energy transition

Zurich, Switzerland, June 28, 2022 (GLOBE NEWSWIRE) — Hitachi Energy a market and technology leader in transmission, distribution and grid automation solutions, and Petrofac, a leading international service provider to the energy industry, have entered into a collaboration to provide grid integration and associated infrastructure to support the rapidly growing offshore wind market.

This collaboration builds on the complementary core technologies and expertise of both companies in offshore wind to support the decarbonization of power systems and deliver clean energy. It covers high-voltage direct current (HVDC), as well as high-voltage alternating current (HVAC) solutions.

Hitachi Energy’s HVDC Light® and modular HVAC grid technologies and solutions and Petrofac’s world-class engineering, procurement, construction and installation capabilities for offshore platforms and offshore and onshore civil works, will bring considerable benefits to the efficient implementation of offshore wind projects and help accelerate the energy transition.

“We are delighted to collaborate with Petrofac to help meet the growing need for large-scale offshore wind generation and deliver clean renewable electricity to consumers. As leaders in our respective fields, this collaboration will create added value for our customers and help accelerate the energy transition,” said Niklas Persson, Managing Director of Hitachi Energy’s Grid Integration business. “Our HVDC and HVAC solutions are key enablers of the transition to a global energy system that is more sustainable, flexible and secure.”

“Offshore wind plays a crucial role in the transition to clean, affordable energy and we’ve been successfully delivering major projects in the sector for more than a decade now,” said Elie Lahoud, Chief Operating Officer, Engineering & Construction of Petrofac. “Hitachi Energy is well known for its long track record in providing innovative technologies and solutions across the power grid value chain. We look forward to bringing our industry-leading experience and deep domain knowledge together, to benefit our customers and power millions more homes using renewable energy.”

Recent Hitachi Energy HVDC offshore wind projects include Dogger Bank, the world’s largest offshore wind farm off the UK coast, and four of the DolWin and BorWin HVDC hubs that connect multiple wind farms in the North Sea to the German power grid.

Hitachi Energy is also a global leading supplier of grid connection solutions for the AC offshore wind farms industry.

Editor’s notes

Offshore wind is undergoing unprecedented growth globally. In 2021, a record 15.7 gigawatts (GW) of capacity were added, compared to around 5.2 GW per year in 2020 and 2019, according to World Forum Offshore Wind.1

Hitachi Energy pioneered HVDC almost 70 years ago and has delivered more than half of the world’s HVDC projects and more than 70 percent of the world’s voltage source converter (HVDC Light) installations. HVDC Light is the technology of choice for transferring power over long distances from offshore wind farms to the mainland grid. Its defining features include uniquely compact converter stations (which is extremely important in space-critical applications like offshore wind platforms), exceptionally low electrical losses of less than 1 percent, and black-start capability to restore power after a grid outage.

  1. https://wfo-global.org/wp-content/uploads/2022/02/WFO_Global-Offshore-Wind-Report-2021.pdf

About Hitachi Energy Ltd.

Hitachi Energy is a global technology leader that is advancing a sustainable energy future for all. We serve customers in the utility, industry and infrastructure sectors with innovative solutions and services across the value chain. Together with customers and partners, we pioneer technologies and enable the digital transformation required to accelerate the energy transition towards a carbon-neutral future. We are advancing the world’s energy system to become more sustainable, flexible and secure whilst balancing social, environmental and economic value. Hitachi Energy has a proven track record and unparalleled installed base in more than 140 countries. Headquartered in Switzerland, we employ around 38,000 people in 90 countries and generate business volumes of approximately $10 billion USD.

https://www.hitachienergy.com

https://www.linkedin.com/company/hitachienergy

https://twitter.com/HitachiEnergy

About Hitachi, Ltd.

Hitachi drives Social Innovation Business, creating a sustainable society with data and technology. We will solve customers’ and society’s challenges with Lumada solutions leveraging IT, OT (Operational Technology) and products, under the business structure of Digital Systems & Services, Green Energy & Mobility, Connective Industries and Automotive Systems. Driven by green, digital, and innovation, we aim for growth through collaboration with our customers. The company’s consolidated revenues for fiscal year 2021 (ended March 31, 2022) totaled 10,264.6 billion yen ($84,136 million USD), with 853 consolidated subsidiaries and approximately 370,000 employees worldwide. For more information on Hitachi, please visit the company’s website at https://www.hitachi.com.

Jocelyn Chang
Hitachi Energy Ltd.
jocelyn.chang@hitachienergy.com

G7 Leaders’ Communiqué – Executive summary

We, the Leaders of the Group of Seven (G7), met in Elmau, Germany, on 26-28 June 2022, were joined by the Leaders of Argentina, India, Indonesia, Senegal and South Africa, as well as Ukraine.

At a time when the world is threatened by division and shocks, we, the G7, stand united. We underscore our resolve to, together with partners, jointly defend universal human rights and democratic values, the rules-based multilateral order, and the resilience of our democratic societies. In doing so, we will address the key challenges of our time:

• We reemphasise our condemnation of Russia’s illegal and unjustifiable war of aggression against Ukraine. We will stand with Ukraine for as long as it takes, providing the needed financial, humanitarian, military, and diplomatic support in its courageous defence of its sovereignty and territorial integrity. We are ready to reach arrangements together with interested countries and institutions and Ukraine on sustained security commitments to help Ukraine defend itself and to secure its free and democratic future.

• Our financial support in 2022 amounts to more than USD 2.8 billion in humanitarian aid, and we are ready to grant, or have pledged and provided USD 29.5 billion in budget aid. We are strongly committed to supporting Ukranian reconstruction through an international reconstruction conference and plan, drawn up and implemented by Ukraine in close coordination with international partners.

• We will continue to impose severe and enduring costs on Russia to help bring an end to this war. Beyond its direct implications, Russia’s aggression is impeding the global recovery and dramatically worsening energy security and access to food globally. To this end, we remain steadfast in our commitment to our unprecedented coordination on sanctions for as long as necessary, acting in unison at every stage, and will reduce Russia’s revenues, including from gold.

• We will help to stabilise and transform the global economy while tackling rising costs of living for our citizens. We will coordinate on our economic security, strengthen the resilience of supply chains and secure a level-playing field.

• We will take immediate action to secure energy supply and reduce price surges driven by extraordinary market conditions, including by exploring additional measures such as price caps. We reaffirm our commitment to phase out our dependency on Russian energy, without compromising on our climate and environmental goals.

• With our partners, we have made significant progress towards the target of USD 100 billion for the most vulnerable, building on the 2021 Special Drawing Rights allocation. To protect people from hunger and malnutrition, and in response to Russia’s weaponisation of grain, we will increase global food and nutrition security through the Global Alliance on Food Security. We will provide an additional USD 4.5 billion to this end, stand by our commitments to keep our food and agricultural markets open and step up efforts to help Ukraine produce and export.

• We endorse the goals of an open and cooperative international Climate Club, and will work with partners towards establishing it by the end of 2022. To drive urgent, ambitious, and inclusive action to align ourselves with 1.5°C pathways and to accelerate implementation of the Paris Agreement, we commit to a highly decarbonised road sector by 2030, a fully or predominantly decarbonised power sector by 2035, and prioritising concrete and timely steps towards the goal of accelerating phase-out of domestic unabated coal power.

• Through our Partnership for Global Infrastructure and Investment, we aim to mobilise USD 600 billion over the next five years to narrow the global investment gap. We will step up our cooperation globally, including through working towards new Just Energy Transition Partnerships with Indonesia, India, Senegal and Vietnam, building on our existing partnership with South Africa.

• To overcome the current COVID-19 pandemic, we will build on our provision of over 1.175 billion vaccine doses since we last met. We will also prevent, prepare, and respond to future pandemics and health challenges including through the G7 Pact for Pandemic Readiness.

• Guided by the conviction that democratic values make us stronger in tackling global challenges, we will cooperate with civil society and our partners beyond the G7 to strengthen the resilience of our societies, promote human rights online and offline, address disinformation, and achieve gender equality.

With these joint commitments and actions taken today, and by working together with partners, we will make progress towards an equitable world.

Source: European Council of the European Union

Stage 6 load shedding from 4pm

Eskom says stage 6 load shedding will be implemented from 4pm to 10pm tonight due to “unlawful industrial action” by some of its personnel at its power stations.

The power utility said the stages of load shedding for Tuesday and Wednesday will be as follows:

• Stage 6 this evening will be followed by stage 4 load shedding between 10pm and midnight.

• From midnight until 5am on Wednesday morning, Eskom will implement stage two load shedding.

• From 5am on Wednesday, stage 4 will return until 4pm.

• From 4pm, the power utility will once again implement stage six load shedding until 10pm on Wednesday.

“This is due to the unlawful and unprotected labour action, which has caused widespread disruption to Eskom’s power plants. This has compelled Eskom to continue taking precautionary measures to conserve generation capacity and safeguard plants from damage.

“Eskom continues to closely monitor the system, adjust and communicate any changes as may be necessary. We appeal to all South Africans to help limit the impact of the shortages by continuing to reduce the usage of electricity and to switch off all non-essential items,” the power utility said.

Eskom said at least three generation units, which were part of a cohort of 10 which broke down overnight, have been brought back online.

“This, however, is still insufficient to stave off the implementation of Stage six load shedding for this evening and tomorrow evening. We currently have 3 218MW [of power] on planned maintenance, while another 17 621MW of capacity is unavailable due to breakdowns.

“We would like to remind the public that load shedding is implemented only as a last resort to protect the national grid. We therefore urge all South Africans to continue using electricity sparingly especially during these uncertain times on the power system,” Eskom said.

Source: South African Government News Agency

Rapid response services in Gauteng continue to clamp down on crime in the province

PARKTOWN - Within a period of seven days (17 to 23 June 2022), members of Rapid Response Services (RRS) in Gauteng arrested 176 suspects and recovered 58 stolen motor vehicles and nine unlicensed firearms across the province.

The Rapid Response Services component comprises of units such as Flying Squad, K9 Unit and Gauteng Highway Patrol.

The 176 suspects arrested during various crime prevention operations are facing charges that include among others: murder; assault with intent to cause grievous bodily harm; rape; theft; tampering with essential infrastructure; possession of drugs, stolen property and unlicensed firearms.

The suspects are appearing before the various local Magistrates' courts across the province.

Source: South African Police Service

Load shedding could be pushed to stage 6, says Eskom

Eskom CEO Andre de Ruyter says further challenges in generation capacity mean that there is a strong possibility that the country will have to move into stage 6 load shedding from tonight.

The power utility suffered breakdowns of 10 generating units overnight, resulting in the loss of more than 6 000MW of power. By Tuesday morning, only 1 300MW of power has been returned to the grid.

Furthermore, the power utility is already facing a deficit of some 1 400MW of power ahead of the evening peak, despite implementing stage 4 load shedding since Friday.

De Ruyter said at least 14 204MW of power is currently unavailable due to breakdowns, with an additional 3 218MW also offline due to planned maintenance.

“We have associated losses mainly due to the unavailability of coal and labour, which leads us to an addition 3661MW of capacity that is not available. This situation creates substantial risk. We currently have plans to return some 3 400MW to service by 5pm this afternoon.

“If we get all of that back – and that is subject to considerable risk, given the nature of the ongoing unlawful industrial action that we are experiencing – there is a possibility that we may avert to stage six [load shedding]. But the risk is there,” he said on Tuesday.

De Ruyter said the power utility has also been relying heavily on its reserves.

“We have been consuming considerable diesel over the past number of days. We are burning about two million litres of diesel per day at both Ankerlig as well as Gourikwa [open cycle gas turbines]. For the month of June to date, we have already consumed 85 million litres of diesel.

“We need to protect both our dams and our diesel reserves in order to maintain that vital reserves capacity in the event of further unit outages,” he said.

Industrial action

The chief executive said the ongoing strike at Eskom is further crippling its ability to ensure that power stations are manned and electricity is supplied.

“At Arnot [power station], we have no bargaining unit employees available and we are running with our managerial staff. At Camden similarly, our control rooms are manned by managerial staff. There has been a blocking of the access road by the dumping of coal… onto the access road. At Duvha, we have no controllers on site. At Hendrina, only 20% of workers are on site.

“We have seen peaceful protest at Kendal and Komati, where only one unit is operating. At Kriel, we have seen peaceful protesting but we have seen no resources for ash and dust handling and no plant operators. At Lethabo, we have seen pretty severe incidents of intimidation… 70 maintenance staff are absent,” De Ruyter said.

At least seven other power stations have experienced minimal to no strike related incidents.

De Ruyter said Eskom is diverting staff to keep essential services running but this has left the power utility unable to perform maintenance on plants.

“If the strike is resolved, we will have a significant backlog in maintenance, which will further create a prolonged risk of load shedding.

“I personally engaged with union leadership [on Monday]. We have had a productive discussion. We are in the process of preparing for another meeting… and if we are able to resolve the matter, then it will be a question of a number of shifts before we have all our people back on site and restoring the situation,” he said.

Source: South African Government News Agency